{"id":5455,"date":"2024-11-13T09:12:26","date_gmt":"2024-11-13T07:12:26","guid":{"rendered":"https:\/\/healthandfood.taltech.ee\/?post_type=research&#038;p=5455"},"modified":"2025-04-29T18:16:54","modified_gmt":"2025-04-29T15:16:54","slug":"research-group-of-metalloproteomics","status":"publish","type":"research","link":"https:\/\/healthandfood.taltech.ee\/en\/researches\/research-group-of-metalloproteomics\/","title":{"rendered":"Research group of metalloproteomics"},"content":{"rendered":"<p>The Research Group of Metalloproteomics is focused on the following topics:<\/p>\n<ol>\n<li>Structural and functional studies of metalloproteins participating in homeostasis of biometals: zinc, copper and iron by methods like NMR, ESI MS, ICP MS, fluorescence ja UV-VIS spectroscopy;<\/li>\n<li>The role of biometals: zinc, copper and iron on fibrillization as well as on in vitro and in vivo toxicity of amyloigogenic peptides linked with Alzheimer\u2019s disease;<\/li>\n<li>Design of new metal-chelating ligands and elaboration of metal-chelating therapeutic strategies for Wilsons and Alzheimer\u2019s disease.<\/li>\n<\/ol>\n<p>Professor Palumaa is a member of the European Molecular Biology Organization (EMBO).<\/p>\n<p>The most important achievements of the research group during last year were connected with the elucidation of the influence of \u03b1-lipoic acid on cellular copper metabolism and evaluation of its therapeutic potential in Alzheimer\u2019s disease insect models.<\/p>\n<p style=\"display: none;\">Alzheimer\u00b4s disease, \u200bbiometals, copper, Wilson\u2019s disease, zinc<\/p>\n","protected":false},"template":"","tags":[1502,1503,1508,1517,1771],"research_cat":[2057],"class_list":["post-5455","research","type-research","status-publish","hentry","tag-copper","tag-biometals","tag-alzheimers-disease","tag-wilsons-disease","tag-zinc","research_cat-faculty-of-science"],"acf":{"research_manager":4901,"related_team":[4346,4637,4408,4844,4500,4268,4222]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research group of metalloproteomics - Health and Food Technologies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/healthandfood.taltech.ee\/en\/researches\/research-group-of-metalloproteomics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research group of metalloproteomics - Health and Food Technologies\" \/>\n<meta property=\"og:description\" content=\"The Research Group of Metalloproteomics is focused on the following topics: Structural and functional studies of metalloproteins participating in homeostasis of biometals: zinc, copper and iron by methods like NMR, ESI MS, ICP MS, fluorescence ja UV-VIS spectroscopy; 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