{"id":6530,"date":"2025-03-25T12:41:08","date_gmt":"2025-03-25T10:41:08","guid":{"rendered":"https:\/\/healthandfood.taltech.ee\/?post_type=research&#038;p=6530"},"modified":"2026-03-04T16:25:32","modified_gmt":"2026-03-04T14:25:32","slug":"neuroepigenetics","status":"publish","type":"research","link":"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/","title":{"rendered":"Neuroepigenetics"},"content":{"rendered":"<p>The laboratory of neuroepigenetics studies how epigenetic mechanisms control neuronal development and function throughout life. Neurons are born and mature early in development and are typically not replaced during the organism&#8217;s lifetime.\u00a0Therefore, once neurons have matured and become fully functional, they must remain so for a long time &#8211; in humans, for up to a hundred years or more. This means that the transcriptional programs that become established during neuronal maturation must remain stable &#8211; yet responsive to external stimuli &#8211; over the entire lifespan of an organism.<\/p>\n<p>We are interested in how the epigenetic landscape is set up and controls transcriptional programs in during neuronal maturation and how epigenetic and transcriptional stability are maintained in neurons throughout life.<\/p>\n<p>The main research directions are studying the role of histone bivalency, H3K27me3, and methyltransferase EZH1 in neuronal development and ageing.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"display: none;\">ageing, bivalency, development, epigenetics, histone modifications, neurons<\/p>\n","protected":false},"template":"","tags":[1957,1958,1960,1961,2084,2085],"research_cat":[2057],"class_list":["post-6530","research","type-research","status-publish","hentry","tag-ageing","tag-neurons","tag-epigenetics","tag-histone-modifications","tag-development","tag-bivalency","research_cat-faculty-of-science"],"acf":{"research_manager":6674,"related_team":[4207]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neuroepigenetics - Health and Food Technologies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neuroepigenetics - Health and Food Technologies\" \/>\n<meta property=\"og:description\" content=\"The laboratory of neuroepigenetics studies how epigenetic mechanisms control neuronal development and function throughout life. Neurons are born and mature early in development and are typically not replaced during the organism&#8217;s lifetime.\u00a0Therefore, once neurons have matured and become fully functional, they must remain so for a long time &#8211; in humans, for up to a [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/\" \/>\n<meta property=\"og:site_name\" content=\"Health and Food Technologies\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-04T14:25:32+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/researches\\\/neuroepigenetics\\\/\",\"url\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/researches\\\/neuroepigenetics\\\/\",\"name\":\"Neuroepigenetics - Health and Food Technologies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/#website\"},\"datePublished\":\"2025-03-25T10:41:08+00:00\",\"dateModified\":\"2026-03-04T14:25:32+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/researches\\\/neuroepigenetics\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/researches\\\/neuroepigenetics\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/researches\\\/neuroepigenetics\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Neuroepigenetics\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/\",\"name\":\"Tervise- ja toidutehnoloogiate fookustippkeskus\",\"description\":\"Health and food technology activities\",\"publisher\":{\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/#organization\",\"name\":\"TalTech\",\"url\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/wp-content\\\/uploads\\\/2024\\\/12\\\/cropped-taltech-favorites.webp\",\"contentUrl\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/wp-content\\\/uploads\\\/2024\\\/12\\\/cropped-taltech-favorites.webp\",\"width\":512,\"height\":512,\"caption\":\"TalTech\"},\"image\":{\"@id\":\"https:\\\/\\\/healthandfood.taltech.ee\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Neuroepigenetics - Health and Food Technologies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/","og_locale":"en_US","og_type":"article","og_title":"Neuroepigenetics - Health and Food Technologies","og_description":"The laboratory of neuroepigenetics studies how epigenetic mechanisms control neuronal development and function throughout life. Neurons are born and mature early in development and are typically not replaced during the organism&#8217;s lifetime.\u00a0Therefore, once neurons have matured and become fully functional, they must remain so for a long time &#8211; in humans, for up to a [&hellip;]","og_url":"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/","og_site_name":"Health and Food Technologies","article_modified_time":"2026-03-04T14:25:32+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/","url":"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/","name":"Neuroepigenetics - Health and Food Technologies","isPartOf":{"@id":"https:\/\/healthandfood.taltech.ee\/en\/#website"},"datePublished":"2025-03-25T10:41:08+00:00","dateModified":"2026-03-04T14:25:32+00:00","breadcrumb":{"@id":"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/healthandfood.taltech.ee\/en\/researches\/neuroepigenetics\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/healthandfood.taltech.ee\/en\/"},{"@type":"ListItem","position":2,"name":"Neuroepigenetics"}]},{"@type":"WebSite","@id":"https:\/\/healthandfood.taltech.ee\/en\/#website","url":"https:\/\/healthandfood.taltech.ee\/en\/","name":"Tervise- ja toidutehnoloogiate fookustippkeskus","description":"Health and food technology activities","publisher":{"@id":"https:\/\/healthandfood.taltech.ee\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/healthandfood.taltech.ee\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/healthandfood.taltech.ee\/en\/#organization","name":"TalTech","url":"https:\/\/healthandfood.taltech.ee\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/healthandfood.taltech.ee\/en\/#\/schema\/logo\/image\/","url":"https:\/\/healthandfood.taltech.ee\/wp-content\/uploads\/2024\/12\/cropped-taltech-favorites.webp","contentUrl":"https:\/\/healthandfood.taltech.ee\/wp-content\/uploads\/2024\/12\/cropped-taltech-favorites.webp","width":512,"height":512,"caption":"TalTech"},"image":{"@id":"https:\/\/healthandfood.taltech.ee\/en\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/research\/6530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/research"}],"about":[{"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/types\/research"}],"acf:post":[{"embeddable":true,"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/member\/4207"},{"embeddable":true,"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/member\/6674"}],"wp:attachment":[{"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/media?parent=6530"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/tags?post=6530"},{"taxonomy":"research_cat","embeddable":true,"href":"https:\/\/healthandfood.taltech.ee\/en\/wp-json\/wp\/v2\/research_cat?post=6530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}