Merike Vaher

The rapid emergence of new illegal drugs (HHC, nitazenes, synthetic cathinones, etc.) creates a need for fast, on-site drug testing tools that can detect multiple substances in biofluids. These tools are crucial for clinicians, anti-doping experts, and law enforcement. Multiplexed portable analytical tools have a great potential to be implemented for this purposes. Moreover, such kind of instruments could be utilized in personal healthcare monitoring by enabling early-stage diagnostics of health problems. This project aims to develop electrophoresis-based analytical tools for reliable, fast and cost-effective metabolism studies in vitro, revealing the characteristics and metabolic pathways of new psychoactive substances. Additionally, new on-site biofluid testing tools (focused on oral fluid) will be developed for detecting new drugs. The results of this project will enhance drug monitoring, support public health, and improve safety.

Georgia produces about 70 thousand tonnes of mandarins annually, 50% of which gets exported. Local fruit juice industry utilizes most of the mandarins left in the country to produce mandarin juice. However, the leftover mandarin pomace causes serious environmental issues as the piled up pomace waste leaches acidic decomposting products as well as essential oils into the environment. Mandarin pomace is a rich source of fine chemicals and the project will develop environmentally friendly technologies to extrat those chemicals from the waste.