Analytical chemistry

The rapid emergence of new illegal drugs (HHC, nitazenes, synthetic cathinones, etc.) creates a need for fast, on-site drug testing tools that can detect multiple substances in biofluids. These tools are crucial for clinicians, anti-doping experts, and law enforcement. Multiplexed portable analytical tools have a great potential to be implemented for this purposes. Moreover, such kind of instruments could be utilized in personal healthcare monitoring by enabling early-stage diagnostics of health problems. This project aims to develop electrophoresis-based analytical tools for reliable, fast and cost-effective metabolism studies in vitro, revealing the characteristics and metabolic pathways of new psychoactive substances. Additionally, new on-site biofluid testing tools (focused on oral fluid) will be developed for detecting new drugs. The results of this project will enhance drug monitoring, support public health, and improve safety.

Wood is Estonia's most important bio-based raw material, the skilful processing of which creates high added value, carbon binding products. Today, Estonian universities do not have a unified action plan and infrastructure for coordinated research and development (R&D) and for offering industrial solutions throughout the entire value chain. Therefore, the infrastructure is created for linking 14 structural units of 8 institutes of 3 universities. This synergy enables to carry out interdisciplinary, high quality R&D activities of wood valorisation. The infrastructure creates new opportunities for training young researchers and provides a strong base for international cooperation. An integrated contact point will be created for effective marketing of services of the infrastructure. R&D of the infrastructure covers mechanical, chemical, biochemical and thermochemical valorisation of primary and secondary wood and can take the Estonian wood science and industry to a new development level.

Wood or lignocellulosic biomass more generally, is a readily available renewable resource, offering sustainable solutions for our growing human population. The core wood polymers - cellulose, hemicellulose, and lignin - serve as fundamental components, extending beyond paper production to produce valuable wood sugars, textile fibers, thermoplastics, and fine chemicals. In our project, we are developing enzyme technologies utilizing extremophilic microbe-derived enzymes to break down and modify lignin, remove toxic phenolic compounds, convert cellulose into wood sugars, and advance enzyme-catalyzed cellulose technologies. Additionally, the project focuses on advancing technologies for converting kraft, hydrolysis (and organosolv) and synthetic lignins into porous materials, thermoplastics, and cutting-edge catalysts.