Publikatsioonid

Stimulus-Dependent Expression of Bdnf Is Mediated by ATF2, MYT1L, and EGR1 Transcription Factors
Väljaanne: Journal of Neuroscience
Autorid: Esvald, Eli-Eelika; Moistus, Andra; Lehe, Karin; Avarlaid, Annela; Subina, Anastassia; Kuusemets, Liis; Tuvikene, Jurgen; Timmusk, Tonis
Aasta: 2025
Higher AMPK activation in mouse oxidative compared with glycolytic muscle does not correlate with LKB1 or CaMKKb expression
Väljaanne: American Journal of Physiology. Endocrinology and Metabolism
Autorid: Bernasconi, R.; Soodla, K.; Sirp, A.; Zovo, K.; Kuhtinskaja, M.; Lukk, T.; Vendelin, M.; Birkedal, R.
Aasta: 2025
An 840 kb distant upstream enhancer is a crucial regulator of catecholamine-dependent expression of the Bdnf gene in astrocytes
Väljaanne: Glia
Autorid: Avarlaid, Annela; Esvald, Eli‐Eelika; Koppel, Indrek; Parkman, Annabel; Zhuravskaya, Anna; Makeyev, Eugene V.; Tuvikene, Jürgen; Timmusk, Tõnis
Aasta: 2024
An upstream enhancer and MEF2 transcription factors fine-tune the regulation of the Bdnf gene in cortical and hippocampal neurons
Väljaanne: Journal of Biological Chemistry
Autorid: Avarlaid A.; Falkenberg K.; Lehe K.; Mudò G.; Belluardo N.; Di Liberto V.; Frinchi M.; Tuvikene J.; Timmusk T.
Aasta: 2024
Electrochemical sensor based on molecularly imprinted polymer for rapid quantitative detection of brain-derived neurotrophic factor
Väljaanne: Sensors and Actuators B: Chemical
Autorid: Ayankojo, Akinrinade George; Boroznjak, Roman; Reut, Jekaterina; Tuvikene, Jürgen; Timmusk, Tõnis; Syritski, Vitali
Aasta: 2023
2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer’s resilience
Väljaanne: Neuron
Autorid: Kumar, Amit; Karuppagounder, Saravanan S.; Chen, Yingxin; Corona, Carlo; Kawaguchi, Riki; Cheng, Yuyan; Balkaya, Mustafa; Sagdullaev, Botir T.; Wen, Zhexing; Stuart, Charles; Cho, Sunghee; Ming, Guo-li; Tuvikene, Jürgen; Timmusk, Tõnis; Geschwind, Daniel H.; Ratan, Rajiv R.
Aasta: 2023
Untranslated regions of brain-derived neurotrophic factor (Bdnf) mRNA control its translatability and subcellular localization
Väljaanne: Journal of Biological Chemistry
Autorid: Lekk, I.; Cabrera-Cabrera, F.; Turconi, G.; Tuvikene, J.; Esvald, E.-E.; Rähni, A.; Casserly, L.; Garton, D. R.; Andressoo, J.-O.; Timmusk, T.; Koppel, I.
Aasta: 2023
PCSK9 deficiency alters brain lipid composition without affecting brain development and function
Väljaanne: Frontiers in Molecular Neuroscience
Autorid: Pärn, Angela; Olsen, Ditte; Tuvikene, Jürgen; Kaas, Mathias; Borisova, Ekaterina; Bilgin, Mesut; Elhauge, Mie; Vilstrup, Joachim; Madsen, Peder; Ambrozkiewicz, Mateusz C.; Goz, Roman U.; Timmusk, Tõnis; Tarabykin, Victor; Gustafsen, Camilla; Glerup, Simon
Aasta: 2023
Revisiting the expression of BDNF and its receptors in mammalian development
Väljaanne: Frontiers in Molecular Neuroscience
Autorid: Esvald, Eli-Eelika; Tuvikene, Jürgen; Kiir, Carl Sander; Avarlaid, Annela; Tamberg, Laura; Sirp, Alex; Shubina, Anastassia; Cabrera-Cabrera, Florencia; Pihlak, Arno; Koppel, Indrek; Palm, Kaia; Timmusk, Tõnis
Aasta: 2023
Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individuals
Väljaanne: Scientific Reports
Autorid: Jaago, Mariliis; Rähni, Annika; Pupina, Nadežda; Pihlak, Arno; Sadam, Helle; Tuvikene, Jürgen; Avarlaid, Annela; Planken, Anu; Planken, Margus; Haring, Liina; Vasar, Eero; Baćević, Miljana; Lambert, France; Kalso, Eija; Pussinen, Pirkko; Tienari, Pentti J.; Vaheri, Antti; Lindholm, Dan; Timmusk, Tõnis; Ghaemmaghami, Amir M. ... Palm, Kaia
Aasta: 2022
Expression of alternative transcription factor 4 mRNAs and protein isoforms in the developing and adult rodent and human tissues
Väljaanne: Frontiers in Molecular Neuroscience
Autorid: Sirp, A.; Shubina, A.; Tuvikene, J.; Tamberg, L.; Kiir, C. S.; Kranich, L.; Timmusk, T.
Aasta: 2022
Differential regulation of the BDNF gene in cortical and hippocampal neurons
Väljaanne: Journal of Neuroscience
Autorid: Esvald, E.-E.; Tuvikene, J.; Moistus, A.; Rannaste, K.; Kõomägi, S.; Timmusk, T.
Aasta: 2022
Immune response to a conserved enteroviral epitope of the major capsid VP1 protein is associated with lower risk of cardiovascular disease
Väljaanne: EBioMedicine
Autorid: Pupina, N.; Avarlaid, A.; Sadam, H.; Pihlak, A.; Jaago, M.; Tuvikene, J.; Rähni, A.; Planken, A.; Planken, M.; Kalso, E.; Tienari, P.J.; Nieminen, J.K.; Seppänen, M.R.J.; Vaheri, A.; Lindholm, D.; Sinisalo, J.; Pussinen, P.; Timmusk, T.; Palm, K.
Aasta: 2022
Melanoma-specific antigen-associated antitumor antibody reactivity as an immune-related biomarker for targeted immunotherapies